Ebastine + Montelukast Sodium – Dual Action for Allergy & Asthma Relief

Ebastine is a fast-acting, non-sedating second-generation antihistamine designed to provide long-lasting relief from various allergic conditions. Its once-daily dosage effectively inhibits histamine-induced wheal and flare, making it a dependable choice for maintaining an active lifestyle despite allergies. This advanced formulation reduces serum eosinophil cationic protein levels in asthma patients and demonstrates a quicker onset and superior efficacy compared to Cetirizine 10 mg, especially in those with more severe symptoms. Additionally, Ebastine boosts IFN-gamma production, a key indicator of clinical immunological improvement.

Montelukast Sodium, a potent leukotriene receptor antagonist, works by blocking cysteinyl leukotrienes — substances responsible for inflammation, bronchoconstriction, and other allergic symptoms. It complements Ebastine’s action by targeting the inflammatory pathway, making the combination especially effective for respiratory allergies and asthma.

Key Advantages

• Single dose inhibits histamine-induced wheal and flare
• Reduces serum eosinophil cationic protein levels in asthma patients
• Ebastine have advantages over cetirizine 10 mg in terms of a reduced time to achieve maximal efficacy and a superior level of efficacy in patients with more severe symptoms
• Increases IFN-gamma production — supporting immune system response

Indications

This combination is indicated for the symptomatic treatment of:

• Seasonal and perennial rhinitis or conjunctivitis
• Allergic dermatitisChronic urticaria
• Allergic dermatitis
• Atopic dermatitis
• Exercise-induced bronchoconstriction
• Prophylaxis and chronic treatment of asthma